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Plasma levels of aspirin following effervescent and enteric coated tablets, and their effect on platelet function

✍ Scribed by L. M. Ross-Lee; M. J. Elms; B. E. Cham; F. Bochner; I. H. Bunce; M. J. Eadie


Publisher
Springer
Year
1982
Tongue
English
Weight
807 KB
Volume
23
Category
Article
ISSN
0031-6970

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Administration of L-dopa (L-3,4-dihydroxyphenylalanine) (200 mg/kg p.o.) to rats produced elevated plasma and muscle concentrations of both L-dopa and 3-O-methyldopa (3-OMD). This effect was potentiated by simultaneous administration of carbidopa (25 mg/kg p.o.). Both L-dopa and 3-OMD accumulated in