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Plasma islet amyloid polypeptide measurements: studies in man and transgenic mice.

✍ Scribed by van Hulst, K


Book ID
122464051
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
224 KB
Volume
47
Category
Article
ISSN
0300-2977

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Transgenic mice overproducing islet amyl
✍ C. B. Verchere; D. A. D'Alessio; R. D. Palmiter; S. E. Kahn πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 392 KB

To determine whether chronic overproduction of islet amyloid polypeptide alters beta-cell function, we studied a line of transgenic mice which overexpress islet amyloid polypeptide in their beta-cells. At 3 months of age, these transgenic mice had greater pancreatic content of both islet amyloid pol