Plasma free N-terminal fibronectin 30-kDa domain as a marker of endothelial dysfunction in type 1 diabetes mellitus

Evidence for the presence of a free N-te

Evidence for the presence of a free N-terminal fibronectin 30-kDa domain in human plasma by quantitative determination with an indirect immunosorbent assay

✍ Jan Škrha; Hartmut Richter; Helmut Hörmann 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 627 KB

The free N-terminal 30-kDa domain of the fibronectin subunit chains had previously been shown to mediate binding of soluble fibrin to phagocytic cells. In order to demonstrate whether the fragment is available in plasma in a suitable concentration, an indirect immunoassay procedure for its quantitat