Plasma fibronectin concentrations in healthy newborns and in children

✍ Scribed by E. A. Valletta; L. Bonazzi; R. Zuanazzi; G. Col; A. Andreoli; L. Stocchero; A. L. Boner

• Publisher: Springer
• Year: 1988
• Tongue: English
• Weight: 307 KB
• Volume: 147
• Category: Article
• ISSN: 0340-6997
• DOI: 10.1007/bf00442615

✦ Synopsis

Plasma fibronectin (FN) concentrations were measured by an immunonephelometric method in cord blood from 76 healthy newborns (45 full term and 31 preterm), in 181 healthy children, from 1 month-15 years old, divided by age into seven groups and in 81 control adults. FN levels in newborns were 35% of those of adults. There was no difference between plasma FN in term and preterm (gestational age > 30 weeks) infants. Preterm newborns below the gestational age of 30 weeks showed particularly low FN levels. No clear correlation was seen with birth weight. In the child population, a strong increase in FN values was noted in the first 6 months of life, rising to 65% of the normal adult values. No further increase occurred until puberty.