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Plasma factor Xa-inhibitory activity in alcoholic liver disease and the effect of heparin

✍ Scribed by Panos Gavrilis; Robert G. Lerner; Robert Goldstein

Book ID
119033046
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
486 KB
Volume
4
Category
Article
ISSN
0049-3848

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The synthesis of tri-N-acetylated heparin pentasaccharide 2 is described. It was assembled from five suitably blocked monosaccharide units (S7). Glucuronic-acid building block 4 was prepared from glucose by direct Jones oxidation of the 6-0-trityl derivative 18. The resulting acid 16 was esterified