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Plasma exchange: A controlled study of the effect in patients with Raynaud's phenomenon and scleroderma

✍ Scribed by Mark A. McCune; R. K. Winkelmann; Philip J. Osmundson; Alvaro A. Pineda

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
735 KB
Volume
1
Category
Article
ISSN
0733-2459

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✦ Synopsis

Six female patients with stage 1 and I1 vascular scleroderma and Raynaud's phenomenon were treated with plasma exchange and placebo plasma exchange. Placebo exchange consisted of the return of the patient's own separated plasma. N o consistent long-term objective improvement was demonstrated in patients treated with either plasma exchange or placebo plasma exchange. Immediate increases in pulse volume. digital blood pressure. and skin temperature occurred in some patients with both procedures. Mechanisms of change remain unexplained, and further study Is warranted.

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