๐”– Bobbio Scriptorium
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Plasma diazepam and desmethyldiazepam concentrations during long-term diazepam therapy.

โœ Scribed by DJ Greenblatt; TP Laughren; MD Allen; JS Harmatz; RI Shader

Book ID
117942479
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
641 KB
Volume
11
Category
Article
ISSN
0306-5251

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๐Ÿ“œ SIMILAR VOLUMES

Binding of diazepam and desmethyldiazepa
Binding of diazepam and desmethyldiazepam to plasma protein: Concentration-dependence and interactions
โœ Marcia Divoll; David J. Greenblatt ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Springer ๐ŸŒ English โš– 279 KB

The binding of diazepam (DZ) and its major metabolite desmethyldiazepam (DMDZ) to plasma protein was evaluated in a series of controlled in vitro studies using equilibrium dialysis. Free fraction (FF) of both drugs alone changed significantly with total plasma drug concentration, but the increased F