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Plasma concentrations of nicotine in rats during tolerance and chronic exposure studies

โœ Scribed by B. F. Thomas; E. R. Bowman; S. M. Tucker; M. D. Aceto


Book ID
113006708
Publisher
Springer-Verlag
Year
1988
Tongue
English
Weight
672 KB
Volume
13
Category
Article
ISSN
0378-7966

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The effect of different chronic nicotine administration regimens on body weight and the development of tolerance was examined in female rats. Groups of animals were either treated with nicotine via a subcutaneous continuous release pellet or via two injections each day of either a high (5.6 mg/kg) o