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Plasma clearance and tissue distribution of recombinant human platelet-derived growth factor (B-chain homodimer) in rats

✍ Scribed by Arthur M. Cohen; Carol Soderberg; Arlen Thomason


Book ID
116010619
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
747 KB
Volume
49
Category
Article
ISSN
0022-4804

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In this study we analyzed the expression of mRNA for PDGF-B and PDGF B-type receptor (PDGFrecB) in 42 biopsy specimens from human astrocytic gliomas and other brain tumors. All gliomas expressed PDGF-B mRNA at higher levels than found in peritumoral and normal nervous tissues. Levels of PDGF-B trans