Plasma cell leukemia: advantages of treatment with bortezomib
β Scribed by N. Fraimout; B. Kadouch; M. Ticchioni; N. Mounier
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 73 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1776-2596
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## Abstract ## BACKGROUND. The prognosis of patients with plasma cell leukemia (PCL), an aggressive variant of multiple myeloma (MM), is usually poor. Bortezomib is the first proteasome inhibitor approved for the treatment of advanced MM. Currently available information regarding the role of borte
## Abstract Plasma cell leukemia (PCL) represents the most aggressive form of monoclonal gammopathy for which new treatment approaches are needed. Here we report the effect of Bortezomib on cells from 4 patients with PCL, as well as the __in vivo__ efficacy on a patient with secondary PCL. Bortezom