This study tracks the fate of antigen-reactive B cells through follicular and extrafollicular responses and addresses the function of CD40 in these processes. The unique feature of this system is the use of transgenic B cells in which the heavy chain locus has been altered by site-directed insertion
✦ LIBER ✦
Plasma cell differentiation in T-independent type 2 immune responses is independent of CD11chigh dendritic cells
✍ Scribed by Katrin Hebel; Klaus Griewank; Ayako Inamine; Hyun-Dong Chang; Brigitte Müller-Hilke; Simon Fillatreau; Rudolf A. Manz; Andreas Radbruch; Steffen Jung
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 340 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0014-2980
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## Abstract Our aim was to examine the involvement of G~1~ cell‐cycle regulators in cell growth dysregulation induced by HTLV‐I. Compared to uninfected cells, higher expression levels of cyclin D1 and D2 mRNA were detected in HTLV‐I–infected T‐cell lines, which were at least in part mediated by the