Plasma arginine vasopressin concentrations in epileptics under monotherapy
β Scribed by K. -H. Krause; W. Rascher; P. Berlit
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 209 KB
- Volume
- 230
- Category
- Article
- ISSN
- 0340-5354
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β¦ Synopsis
Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls. No significant difference was found between the groups, but some epileptics taking carbamazepine and primidone showed low values. Serum concentrations of carbamazepine did not correlate with the concentrations of plasma arginine vasopressin. In conclusion, there was no evidence of a stimulating effect of chronic carbamazepine medication or a special inhibiting effect of phenytoin on the release of vasopressin arginine from the posterior pituitary.
π SIMILAR VOLUMES
Cerebrospinal fluid (CSF) arginine vasopressin (AVP) levels are reported in a group of 22 children (median age 24 months) investigated for possible bacterial meningitis and subsequently found not to be suffering from this disease. The mean CSF AVP concentration was 0.80 +/- 0.33 pg/ml. The results o