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Plasma arginine vasopressin concentrations in epileptics under monotherapy

✍ Scribed by K. -H. Krause; W. Rascher; P. Berlit


Publisher
Springer
Year
1983
Tongue
English
Weight
209 KB
Volume
230
Category
Article
ISSN
0340-5354

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✦ Synopsis


Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls. No significant difference was found between the groups, but some epileptics taking carbamazepine and primidone showed low values. Serum concentrations of carbamazepine did not correlate with the concentrations of plasma arginine vasopressin. In conclusion, there was no evidence of a stimulating effect of chronic carbamazepine medication or a special inhibiting effect of phenytoin on the release of vasopressin arginine from the posterior pituitary.


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✍ M. F. Cotton; P. R. Donald; C. Aalbers πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 274 KB

Cerebrospinal fluid (CSF) arginine vasopressin (AVP) levels are reported in a group of 22 children (median age 24 months) investigated for possible bacterial meningitis and subsequently found not to be suffering from this disease. The mean CSF AVP concentration was 0.80 +/- 0.33 pg/ml. The results o