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Plasma 3, 4-dihydroxyphenylglycol (DHPG) and 3-methoxy-4- hydroxyphenylglycol (MHPG) are insensitive indicators of α2-adrenoceptor mediated regulation of norepinephrine release in healthy human volunteers

✍ Scribed by Mika Scheinin; Sakari Karhuvaara; Pirjo Ojala-Karlsson; Antero Kallio; Markku Koulu


Book ID
118345160
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
562 KB
Volume
49
Category
Article
ISSN
0024-3205

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Determination of 3, 4-dihydroxyphenylgly
✍ F. Karege; J.-M. Gaillard; R. Tissot; J.-M. Azorin; M. Valli 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB 👁 2 views

A method for determining plasma 3,4-dihydroxyphenylethyleneglycol (DHPG), a central noradrenaline (NA) metabolite, is described. The method used HPLC with dual coulometric detection set in screen mode of operation. The isolation of DHPG and related catecholamines (noradrenaline, dopamine and dihydro