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Plaque-forming cells in autoimmune thyroid disease

✍ Scribed by Irene Weiss; Erica De Bernardo; Terry F. Davies

Book ID
118374016
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
516 KB
Volume
23
Category
Article
ISSN
1090-2341

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The elimination of autoreactive T cells in the thymus involves the process of programmed cell death. Animal model studies, using the lpr and gld strains of mice, have identified FAS receptor (FAS) and FAS ligand (FAS-L) as important components of this mechanism. Whether FAS and FAS-L are also implic