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Plant mitochondrial electrical potential monitored by fluorescence quenching of rhodamine 123

✍ Scribed by E. Braidot; E. Petrussa; F. Macrì; A. Vianello

Book ID
111525827
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
401 KB
Volume
41
Category
Article
ISSN
0006-3134

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## Abstract The cancer chemotherapeutic agents 1‐β‐D‐arabinofuranosylcytosine (Ara‐C), methotrexate, and 5‐fluorouracil cause a rapid loss of mitochondrial Rh‐123 uptake in L1210 cells, which correlates with the loss of clonogenic ability. The loss of Rh‐123 uptake is irreversible and occurs prior