Plant anticancer agents XXVII: Antileukemic and cytotoxic constituents of Dirca occidentalis (thymelaeaceae)
✍ Scribed by Mohammed M. Badawi; Sukhdev S. Handa; A. Douglas Kinghorn; Geoffrey A. Cordell; Norman R. Farnsworth
- Book ID
- 102404461
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 418 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0022-3549
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✦ Synopsis
Two antileukemic daphnane esters, Pimelea factor P2 (I) and the new compound dircin (II), were isolated from the twigs and flowers of Dirca occidentalis A. Gray (Thymelaeaceae). Three lignans, (-)-medioresinol (III), (+I-syringaresinol (IV), and (-)-lariciresinol (V), as well as the coumarin daphnoretin (VI), were found to be additional cytotoxic constitents of this taxon.
Keyphrases Dirca occidentalis (Thyme1aeaceae)-isolation of antileukemic and cytotoxic constituents, daphnane esters and lignans, identification 0 Daphnane esters-isolation from Dirca occidentalis (Thymelaeaceae), identification, antileukemic and cytotoxic potential Lignans-isolation from Dirca occidentalis (Thymelaeaceae), identification, antileukemic and cytotoxic potential Antileukemic agents-potential, daphnane esters and lignans isolated from Dirca occidentalis (Thymelaeaceae), cytotoxicity * For the previous article in this series, see Ref. 5.
* Plant extracts, fractions, and isolates were tested under the auspices of the