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Plain radiographic predictors of survival in treated Ewing's sarcoma

✍ Scribed by William R. Reinus; Edmund A. Gehan; Louis A. Gilula; Mark Nesbit

Publisher
Springer
Year
1992
Tongue
English
Weight
908 KB
Volume
21
Category
Article
ISSN
0364-2348

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✦ Synopsis

We analyzed 16 radiographic features of primary Ewing's sarcoma in 342 patients from the IESS 7299 (Intergroup Ewing's Sarcoma Study) for prognostic significance. Of these, 3 features demonstrated a statistically significant relationship to survival: maximal tumor dimension, tumor location, and an appearance of honey-combing within the lesion. Those individuals with primary lesions centered in the pelvis, femur, or humerus had a worse survival rate than those with lesions centered elsewhere. Similarly, we observed an inverse relationship between the greatest dimension of the osseous portion of the lesion and survival. The radiographic finding of honeycombing also showed a statistical association with improved survival. However, this feature was observed infrequently, and its significance should be assessed further. Otherwise, no other feature that we analyzed showed any relationship to patient prognosis.

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