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PLAG1-HAS2 fusion in lipoblastoma with masked 8q intrachromosomal rearrangement

✍ Scribed by Cristina Morerio; Annamaria Rapella; Cristina Rosanda; Elisa Tassano; Claudio Gambini; Giuseppe Romagnoli; Claudio Panarello


Book ID
113512498
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
168 KB
Volume
156
Category
Article
ISSN
0165-4608

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CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusion
✍ Julia Asp; Fredrik Persson; Maria Kost-Alimova; GΓΆran Stenman πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 622 KB

Pleomorphic salivary gland adenomas are characterized by recurrent chromosome rearrangements of 8q12, leading to activation of the PLAG1 oncogene. Here we demonstrate that CHCHD7-PLAG1 is a novel and recurrent gene fusion generated by a cytogenetically cryptic rearrangement in pleomorphic adenomas.