CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusion
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Julia Asp; Fredrik Persson; Maria Kost-Alimova; GΓΆran Stenman
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Article
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2006
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John Wiley and Sons
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English
β 622 KB
Pleomorphic salivary gland adenomas are characterized by recurrent chromosome rearrangements of 8q12, leading to activation of the PLAG1 oncogene. Here we demonstrate that CHCHD7-PLAG1 is a novel and recurrent gene fusion generated by a cytogenetically cryptic rearrangement in pleomorphic adenomas.