Placental thickness in the first half of pregnancy

✍ Scribed by Theera Tongsong; Pongrak Boonyanurak

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 75 KB
• Volume: 32
• Category: Article
• ISSN: 0091-2751
• DOI: 10.1002/jcu.20023

✦ Synopsis

Abstract

Purpose

This study was conducted to establish normal values of placental thickness during the first half of pregnancy.

Methods

Normal pregnant women with singleton pregnancies between 8 and 20 weeks of gestation were recruited into the study. All the newborns were normal at birth. Placental thickness was measured perpendicularly through the thickest part of the placenta on transabdominal scans. The placental thickness data were analyzed for mean, standard deviation, 95% confidence interval, and 2.5^th^, 5^th^, 50^th^, 95^th^, and 97.5^th^ percentile for each week of gestational age. The best‐fit mathematical model was derived by regression analysis.

Results

The total number of measurements was 333 and the number of measurements for each week of gestational age ranged from 9 to 37. Regression analysis yielded the following linear equation of the relationship: placental thickness (in mm) = gestational age (in weeks) × 1.4−5.6 (r = 0.82).

Conclusion

We have established a nomogram for placental thickness. This resource may be a useful aid in the early detection of placental abnormalities, such as hydropic placenta secondary to hemoglobin Bart's disease. © 2004 Wiley Periodicals, Inc. J Clin Ultrasound 32:231–234, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/jcu.20023