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Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

✍ Scribed by Uehara, Yoshihiko; Minowa, Osamu; Mori, Chisato; Shiota, Kohei; Kuno, Junko; Noda, Tetsuo; Kitamura, Naomi

Book ID
109791229
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
654 KB
Volume
373
Category
Article
ISSN
0028-0836

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Sepsis and endotoxemia are involved in the development of fulminant hepatic failure, the prognosis of which is extremely poor and the mortality is high, with no available effective therapy. Here, we report that hepatocyte growth factor (HGF) exerts potent antiapoptotic effects in vivo and effectivel