Placental and lactational transfer of ochratoxin A in rats
✍ Scribed by Ira Palminger Hallén; Anna Breitholtz-Emanuelsson; Karl Hult; Monica Olsen; Agneta Oskarsson
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 65 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1056-9014
No coin nor oath required. For personal study only.
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## Abstract Ochratoxin A (OTA) is a mycotoxin produced by different fungi. The most pronounced adverse effect of OTA is hepatonephrotoxicity. Melatonin (MEL) has an antioxidant effect and has free‐radical scavenger properties. The effects of OTA on heart and lung tissue and possible ameliorating ef
The mycotoxin ochratoxin A (OTA) is a chlorinated dihydroisocoumarin derivative connected through an amide-bond to L-phenylalanine. In a previous study we could show that competition with Lphenylalanine-dependent processes does not play a role in OTA neurotoxicity. To test whether the isocoumarin pa
## Abstract The aim of this study was to find out whether very low doses of nephrotoxic and hepatotoxic mycotoxins ochratoxin A (OTA) and fumonisin B~1~ (FB~1~) induce oxidative stress in rat kidney and liver and whether their effect is synergistic. Rats were treated orally with OTA (5 ng/kg b.w. a