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Placental alkaline phosphatase is related to human IgG internalization in HEp2 cells

โœ Scribed by Ricardo Makiya; Torgny Stigbrand

Book ID
115765562
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
493 KB
Volume
182
Category
Article
ISSN
0006-291X

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Monoclonal antibodies to placental alkal
Monoclonal antibodies to placental alkaline phosphatase: Preclinical evaluation in a human xenograft tumour model of F(ab')2 and Fab fragments
โœ H. Durbin; E. M. Milligan; S. J. Mather; D. F. Tucker; R. Raymond; W. F. Bodmer ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 531 KB

Six new placental alkaline phosphatase monoclonal antibodies (MAbs) have been evaluated in order to select a potentially clinically useful antibody fragment for use in immunoxintigraphy or therapy. Initially, 3 antibodies were identified by trial pepsin digestion as likely to give satisfactory F(ab'