✦ LIBER ✦

Placebo-Controlled trial of paroxetine in depressive illness

✍ Scribed by J. Guy Edwards; Ann Goldie

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 512 KB
Volume: 8
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.470080306

No coin nor oath required. For personal study only.

✦ Synopsis

A randomized double-blind placebotontrolled trial was carried out to assess the effectiveness, tolerance and unwanted effects of paroxetine in the treatment of depressive illness. Forty-one patients referred to a psychiatric unit in a general hospital were included in the study. Treatment lasted for six weeks. The main outcome measures were changes in scores on the Hamilton rating scale for depression and Leeds self-assessment of 'Depression Specific' scale. Statistically significant improvements occurred in both treatment groups, while the end-point differences in scores show significant advantages of paroxetine over placebo.

KEY woms-Paroxetine, placebo, depressive illness.

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