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PL6 - Mathematical modelling of a protein mixture in chromatography applied to high protein concentrations and optimal selection of operating conditions

✍ Scribed by Juan A. Asenjo; Camila A. Orellana; Barbara A. Andrews

Book ID: 113682771
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 53 KB
Volume: 108
Category: Article
ISSN: 1389-1723
DOI: 10.1016/j.jbiosc.2009.08.016

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Mathematical modeling of elution curves

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Elution curves in ionic exchange chromatography (IEC) for a three-protein mixture (alpha-lactoalbumin, ovalbumin, and beta-lactoglobulin), carried out under different flow rates and ionic strength conditions, were simulated using two different mathematical models. These models were the Plate Model a