PKD1haploinsufficiency is associated wit
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Nicole Morel; Greet Vandenberg; Ali K. Ahrabi; Nathalie Caron; Fanny Desjardins;
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Article
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2008
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Springer
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English
โ 405 KB
Mutations in PKD1 are associated with autosomal dominant polycystic kidney disease (ADPKD), which leads to major cardiovascular complications. We used mice with a heterozygous deletion of Pkd1 (Pkd1+/-) and wild-type (Pkd1+/+) littermates to test whether Pkd1 haploinsufficiency is associated with a