PKCϵ induces astrocytic differentiation
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Rivka Steinhart; Gila Kazimirsky; Hana Okhrimenko; Tamir Ben-Hur; Chaya Brodie
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 470 KB
## Abstract In this study, we examined the role of PKC in the differentiation of multipotential neural precursor cells (NPCs). We found that the NPCs expressed PKCα,β2,δ,ϵ,ζ and low levels of PKCγ. The PKC activator, PMA, selectively increased the number of astrocytes, whereas it decreased the gene