𝔖 Bobbio Scriptorium
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PKC controls HGF-dependent c-Met traffic, signalling and cell migration

✍ Scribed by Kermorgant, Stéphanie; Zicha, Daniel; Parker, Peter J


Book ID
110030789
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
633 KB
Volume
23
Category
Article
ISSN
0261-4189

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## Abstract The c‐Met receptor and its ligand scatter factor/hepatocyte growth factor (SF/HGF) are strongly overexpressed in malignant gliomas. Signaling through c‐Met as well as exposure to hypoxia can stimulate glioma cell migration and invasion. In several cancer cell types, hypoxia was shown to