pKa calculations of calbindin D9k: Effects of Ca2+ binding, protein dielectric constant, and ionic strength

15N NMR assignments of (Cd2+,)2-calbindi

15N NMR assignments of (Cd2+,)2-calbindin D9k and comparison with (Ca2+)2-calbindin D9k. Cadmium as a substitute for calcium in calcium-binding proteins

✍ Mikael Akke; Sture Forsén; Walter J. Chazin 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 508 KB

## Abstract The amide ^15^N and ^1^H chemical shifts of (Cd^2+^)~2~‐calbindin D~9k~ are presented. A detailed comparison is made with those of (Ca^2+^)~2~‐calbindin D~9k~, showing that the (Cd^2+^)~2~ and (Ca^2+^)~2~ states of the protein are very similar, with differences predominantly located in