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Pityriasis lichenoides chronica induced by adalimumab therapy for Crohn's disease: Report of 2 cases successfully treated with methotrexate

✍ Scribed by B. Ben Said; J. Kanitakis; I. Graber; J.F. Nicolas; J.C. Saurin; F. Berard

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 88 KB
Volume: 16
Category: Article
ISSN: 1078-0998
DOI: 10.1002/ibd.21110

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✦ Synopsis

Tumor necrosis factor alpha (TNF-a) inhibitors improve inflammatory diseases such as Crohn's disease (CD). However, these biologicals may induce infections, neoplasms, or autoimmune diseases. Cutaneous side effects have been reported, including dermatitis, psoriasis-like rash, and vasculitis. 1 We report the first cases of pityriasis lichenoides chronica (PLC) developed while on adalimumab.