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Pituitary function in a patient with septo-optic dysplasia and pituitary dwarfism (Kaplan-Grumbach-Hoyt syndrome)

✍ Scribed by Magda Kadrnka Lovrenčić; Vlado Oberiter; Zeljka Reiner Banovac; Ljerka Schmutzer; Marijan Petek


Publisher
Springer
Year
1978
Tongue
English
Weight
570 KB
Volume
129
Category
Article
ISSN
0340-6997

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✦ Synopsis


The case of a seventeen-year-old female patient with septo-optic dysplasia and pituitary dwarfism is presented. Mental retardation and epilepsy, in addition to absence of the septum pellucidum, point to a widespread lesion of the central nervous system. There is unilateral hypoplasia of the optic nerve. She is of small stature. The dynamic pituitary tests point to deficiency of GH, TSH and ACTH, and an adequate reserve of prolactin, gonadotrophins and vasopressin. TSH insufficiency is probably of primary pituitary origin.