Estradiol–progesterone interaction durin
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Saleh I. Saleh; Sayed H. Khidr; Sayed M. Ahmed; Theodore M. Jackanicz; Harold A.
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Article
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2003
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John Wiley and Sons
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English
⚖ 185 KB
An unexpected enhanced release, in vitro, of estradiol (E2) was observed on the preparation of vaginal rings containing E2 and progesterone (P) in a silicone elastomer. The present work deals with exploring the reason(s) behind this enhanced E2 release. The effect of the ring design (i.e., putting P