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Pituitary Adenylate Cyclase-Activating Polypeptide Prevents Cytokine-Induced Cytotoxicity via Inhibition of Inducible Nitric Oxide Synthase Expression in βTC Cells

✍ Scribed by Kayo Sekiya; Hiroshi Nagasaki; Nobuaki Ozaki; Atsushi Suzuki; Yoshitaka Miura; Yutaka Oiso


Book ID
115586864
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
140 KB
Volume
278
Category
Article
ISSN
0006-291X

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## Abstract β‐escin, a triterpene saponin, is one of the major active compounds extracted from horse chestnut (__Aesculus hippocastanum__) seed. Previous work has found that β‐escin sodium has antiinflammatory and antitumor effects. In the present study, we investigated its effect on cell prolifera