Pitt-Rogers-Danks syndrome and Wolf-Hirschhorn syndrome
β Scribed by D, Donnai
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 221 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0148-7299
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π SIMILAR VOLUMES
Apparently normal chromosomes without a molecular 4p16.3 deletion were found in a patient with a Wolf-Hirschhorn syndrome (WHS) phenotype. During a 10-year-period of observation he consistently presented with typical facial appearance, moderate to severe mental retardation, normal physical developme
Wolf-Hirschhorn syndrome (WHS), a multiple congenital malformation syndrome, and Pitt-Rogers-Danks syndrome (PRDS), a rare condition with similar anomalies, were previously thought to be clinically distinct conditions. While WHS has long been associated with deletions near the terminus of 4p, severa