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Pioglitazone acutely influences glucose-sensitive insulin secretion in normal and diabetic human islets

✍ Scribed by Fan Zhang; Åke Sjöholm; Qimin Zhang


Book ID
116293866
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
276 KB
Volume
351
Category
Article
ISSN
0006-291X

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Insulin secretion and islet glucose metabolism were compared in pancreatic islets isolated from GK/Wistar (GK) rats with spontaneous Type 2 (non-insulin-dependent) diabetes mellitus and control Wistar rats. Islet insulin content was 24.5 +/- 3.1 microU/ng islet DNA in GK rats and 28.8 +/- 2.5 microU