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Pinning down HER2–ER crosstalk in SMRT regulation

✍ Scribed by Akihide Ryo; Gerburg Wulf; Tae Ho Lee; Kun Ping Lu


Book ID
113931476
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
231 KB
Volume
34
Category
Article
ISSN
0968-0004

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Transgenic mice carrying the HER-2/neu proto-oncogene under tissue-specific transcriptional control of a mammary tumor virus long terminal repeat (Tg-MMTVneu mice) spontaneously develop mammary carcinomas. HER-2/neu is a tumor antigen that can be recognized by cytotoxic T lymphocytes if tumor cells