Histone H1.2 is translocated to mitochon
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Hirohiko Okamura; Kaya Yoshida; Bruna Rabelo Amorim; Tatsuji Haneji
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Article
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2008
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John Wiley and Sons
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English
β 199 KB
## Abstract Bleomycin induces singleβ and doubleβstranded breaks in DNA, with consequent mitochondrial membrane aberrations that lead to the apoptotic cell death. It is poorly understood how DNA damageβinducing apoptotic signals are transmitted to mitochondria, from which apoptotic factors are rele