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PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

✍ Scribed by Sumihiro Kawajiri; Shinji Saiki; Shigeto Sato; Fumiaki Sato; Taku Hatano; Hiroto Eguchi; Nobutaka Hattori


Book ID
113621873
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
969 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract Bleomycin induces single‐ and double‐stranded breaks in DNA, with consequent mitochondrial membrane aberrations that lead to the apoptotic cell death. It is poorly understood how DNA damage‐inducing apoptotic signals are transmitted to mitochondria, from which apoptotic factors are rele