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Pinellic acid from the tuber of Pinellia ternata Breitenbach as an effective oral adjuvant for nasal influenza vaccine

✍ Scribed by Takayuki Nagai; Hiroaki Kiyohara; Kaori Munakata; Tatsuya Shirahata; Toshiaki Sunazuka; Yoshihiro Harigaya; Haruki Yamada


Book ID
117798056
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
275 KB
Volume
2
Category
Article
ISSN
1567-5769

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Total synthesis of pinellic acid, a pote
✍ Toshiaki Sunazuka; Tatsuya Shirahata; Kiminari Yoshida; Daisuke Yamamoto; Yoshih πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 117 KB

Pinellic acid (1), isolated from a medicinal plant Pinelliae tuber, has potent adjuvant activity. The absolute configuration of pinellic acid was expected by derivatization of this compound and CD exciton chirality method. A convergent synthetic route to pinellic acid has been developed via regiosel