Pinealoma. A report of twelve irradiated cases

✍ Scribed by Flora Mincer; Jeffrey Meltzer; Charles Botstein

• Publisher: John Wiley and Sons
• Year: 1976
• Tongue: English
• Weight: 337 KB
• Volume: 37
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197606)37:6<2713::aid-cncr2820370622>3.0.co;2-a

✦ Synopsis

The records of 12 patients with a diagnosis of pinealoma or ectopic pinealoma irradiated a t Montefiore Hospital and Medical Center between 1961 a n d 1971 were reviewed. Diagnosis was made clinically a n d radiographically. Histology is available in three cases. Eight cases were treated with small fields (4 x 4 to 6 x 8 cm), two cases with intermediate, and two with whole brain fields. Doses between 5000 a n d 6000 rads were given by Cobalt-60 or 33 MeV x-rays. Eight patients (66%) show n o evidence of active disease from 4 t o 14 years after irradiation. Of eight patients treated with small fields, seven are free of disease (88%). Of the remainder, 50% a r e free of disease. One patient subsequently developed cerebrospinal spread. The challenge to the radiotherapist is to identify the more aggressive or extensive lesion with the ultimate aim of achieving cure with the most limited treatment.

Cancer 37~2713-2718, 1976.