Pinacol reduction-cum-rearrangement. A re-examination of the reduction of aryl alkyl ketones by zinc–aluminum chloride

✍ Scribed by Anya A. Grant; Myron Allukian; Albert J. Fry

• Book ID: 104251155
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 79 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00737-2

✦ Synopsis

Reduction of alkyl phenyl ketones by zinc and aluminum chloride in acetonitrile results in pinacol condensation followed by rearrangement. The phenyl group migrates in every instance.