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Pilot study of flesinoxan, a 5-HT1A agonist, in major depression

โœ Scribed by Pitchot, W; Ansseau, M; Gonzales Moreno, A; Papart, P; Gerritsen van der Hoop, R; Bradford, D

Book ID
121917689
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
68 KB
Volume
1
Category
Article
ISSN
0924-977X

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Pilot study of flesinoxan, a 5-HT1A agon
Pilot study of flesinoxan, a 5-HT1A agonist, in major depression: Effects on sleep REM latency and body temperature
โœ Marc Ansseau; William Pitchot; Antonio Gonzalez Moreno; Jacques Wauthy; Patrick ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 378 KB ๐Ÿ‘ 1 views

Flesinoxan is a highly potent and selective 5-HTlA full agonist, active in several models of depression. In this pilot open study, flesinoxan (4 mdd) was administered orally for 4 weeks in 16 major depressive, mostly treatmentresistant inpatients exhibiting a score of at least 19 on the Hamilton dep