Pilot study of cyclophosphamide-doxorubicin-vincristine-cisplatin-etoposide hybrid chemotherapy in small cell lung cancer
β Scribed by Taisuke Ohnoshi; Shunkichi Hiraki; Hiroshi Ueoka; Katsuyuki Kiura; Haruhito Kamei; Takashi Horiguchi; Tsuyoshi Kodani; Tadashi Maeda; Masahiro Tabata; Takuo Shibayama; Yoshihiko Segawa; Kazuyo Miyatake; Nagio Takigawa; Ikuro Kimura
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 508 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. To assess whether the addition of cisplatin (100 mg/m 2 administered intravenously on Day 1) to CDE (cyclophosphamide [1000 mg/m 2 on Day 1], doxorubicin [45 mg/m 2 on Day 1], and etoposide [150 mg/m 2 on Days 1 and 2] combination is useful in the treatment of patients with small cel
A total of 39 patients with non-small cell carcinoma of the lung (NSCL) were treated with cisplatin, etoposide, and mitomycin. A major response rate (complete response + partial response) was seen in 15 patients (39%). Median survival for all patients was 340 days; median survival of the responding