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PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma

✍ Scribed by Ali Fendri; Abdelmajid Khabir; Wafa Mnejja; Tahia Sellami-Boudawara; Jamel Daoud; Mounir Frikha; Abdelmonem Ghorbel; Ali Gargouri; Raja Mokdad-Gargouri

Book ID
108586478
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
427 KB
Volume
100
Category
Article
ISSN
1347-9032

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## Abstract The PI3K‐AKT pathway is activated in a variety of human cancers, resulting in disturbance of cell growth, proliferation and survival. Among the factors affecting the pathway, the __K‐Ras__ mutation and __PIK3CA__ mutation are the most common oncogenic alterations in colorectal cancer. W