Pictet-SpenglerSynthesis of Some Thiophene[c]-Fused β-Carbolines
✍ Scribed by Kayed A. Abu Safieh; Basem A. Moosa; Mustafa M. El-Abadelah; Salim S. Sabri; Wolfgang Voelter
- Book ID
- 106213976
- Publisher
- Springer Vienna
- Year
- 2007
- Tongue
- English
- Weight
- 144 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0026-9247
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📜 SIMILAR VOLUMES
## Abstract The synthesis of new pyrazolo[4,3‐__c__]β‐carbolines (**8a,b**) is achieved by condensation of the appropriate aldehyde with 3‐(4‐amino‐1,3‐dimethylpyrazol‐5‐yl)indole (**4**) under Pictet‐Spengler reaction conditions. Regioselective cyclization occurred at the usual indole C‐2 position
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Condensation of 1‐methyl‐β‐carboline‐3‐carbaldehyde with ethyl azidoacetate and subsequent thermolysis of the resulting azidopropenoate was used to [__c__] annulate a pyrrole ring onto the β‐carboline moiety, thus producing the first example of the pyrrolo[3,2‐__c__]‐β‐carboline ring sy