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PICALM Gene rs3851179 Polymorphism Contributes to Alzheimer’s Disease in an Asian Population

✍ Scribed by Guiyou Liu, Shuyan Zhang, Zhiyou Cai, Guoda Ma, Liangcai Zhang…

Book ID: 120897992
Publisher: Humana Press Inc
Year: 2013
Tongue: English
Weight: 334 KB
Volume: 15
Category: Article
ISSN: 1535-1084
DOI: 10.1007/s12017-013-8225-2

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## Abstract Granulin protein plays an important role in neurite outgrowth and neuronal survival. Recently, it was shown that mutations in __granulin__ (__GRN__) gene cause tau‐negative frontotemporal dementia supporting the idea that granulin is involved in neurodegeneration. Here we have investiga