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PI3K/AKT pathway alterations in paired primary and recurrent endometrial carcinoma

✍ Scribed by S. Wethington; K. Garg; V. Makker; N. Olvera; F. Dao; F. Bogomolniy; M. Cesari; R. Soslow; D. Levine

Book ID: 113963566
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 126 KB
Volume: 125
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2011.12.011

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## Abstract We investigated the status of the PI 3‐kinase/AKT/PTEN signaling pathway in a series of 117 head and neck squamous cell carcinomas (HNSCC) in a search for molecular alterations in genes/proteins with potential prognostic value. For this purpose, __PIK3CA__ and __AKT2__ gene amplificatio