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PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane

✍ Scribed by Heo, W. D.; Inoue, T.; Park, W. S.; Kim, M. L.; Park, B. O.; Wandless, T. J.; Meyer, T.

Book ID
118181635
Publisher
American Association for the Advancement of Science
Year
2006
Tongue
English
Weight
863 KB
Volume
314
Category
Article
ISSN
0036-8075

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PI(3,4,5)P3 and PI(4,5)P2 Lipids Target
PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane
✍ Heo, W. D.; Inoue, T.; Park, W. S.; Kim, M. L.; Park, B. O.; Wandless, T. J.; Me πŸ“‚ Article πŸ“… 2006 πŸ› American Association for the Advancement of Scienc 🌐 English βš– 863 KB

Many signaling, cytoskeletal, and transport proteins have to be localized to the plasma membrane (PM) in order to carry out their function. We surveyed PM-targeting mechanisms by imaging the subcellular localization of 125 fluorescent protein–conjugated Ras, Rab, Arf, and Rho proteins. Out of 48 pro