Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor
β Scribed by O'Flynn, Kieran; Krensky, Alan M.; Beverley, Peter C. L.; Burakoff, Steven J.; Linch, David C.
- Book ID
- 109738183
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 233 KB
- Volume
- 313
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/313686a0
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π SIMILAR VOLUMES
he specificity of T-cell recognition events is essential for protective immune responses and in order to avoid autoimmunity. Binding of the T-cell receptor (TCR) to peptide bound to major histocompatibility complex (MHC) molecules is an early step for specific T-cell activation. This engagement lead
## Abstract Phytohemagglutinin (PHA)βstimulated human lymphocytes release soluble products which are mitogenic for other lymphocytes, soβcalled mitogenic factors (MF). MF is highly mitogenic for peripheral T lymphocytes separated by rosetting with sheep red blood cells (SRBC), while being very poor