Bioreactor considerations for secondary
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Gregory F. Payne; Nadine N. Payne; Michael L. Shuler
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Article
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1988
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John Wiley and Sons
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English
โ 790 KB
Batch shake flask studies with Catharanthus roseus demonstrated that alkaloid production commenced only after growth had slowed or ceased. To obtain high alkaloid productivities for extended periods, a hormone-free production medium was used. To develop a readily scalable process, both immobilized a