## Abstract Substantial evidence for involvement of the APUD system in the normal reproductive tract is limited to the prostate gland and uterine cervix. Most supportive data simply documents the presence of neuroβendocrine cells in these tissues. A biological product(s) or role(s) remains to be di
Physiology of the APUD system
β Scribed by Dr. Michael J. Demeure
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 698 KB
- Volume
- 9
- Category
- Article
- ISSN
- 8756-0437
No coin nor oath required. For personal study only.
β¦ Synopsis
The characteristic biochemical pathway of the APUDoma cell, namely amine precursor uptake and decarboxylation, are illustrated by the examples of serotonin and catecholamine metabolism. Increasing understanding of the origins of APUDomas as well as the biochemistry and physiology of the hormones they produce, has led to improved methods of detection, imaging and treatment of afflicted patients.
π SIMILAR VOLUMES
The concept of the APUD system and the APUDomas associated with it has evolved significantly since Pearse's description in the 1960s. Part of this evolution has been an understanding of the relationships between the APUD system and the central and autonomic nervous systems. The APUD system now refer