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Physiologie und Biochemie der Streptomyceten XI. Unterschiedlicher Einbau von D-Glucose-u-14C in die Paromomycin-Isomere und in die Bausteine von Paromomycin I

✍ Scribed by H. Köster; B. Liebermann; Prof. Dr. G. Reuter


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
285 KB
Volume
17
Category
Article
ISSN
0233-111X

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✦ Synopsis


Abstract

During application of D‐glucose‐u‐^14^C paromomycine II is higher labelled and shows a different dependence on the application time than paromomycine I, which is isomer at the paromose part

For the two paromose isomeres different rates of synthesis are supposed that change nonproportionally to each other. The distribution of radioactivity in paromomycine I shows that there is no fragmentation of the glucose chain during the biosynthesis of glucosamine, ribose, and paromose I. As to the 2‐deoxystreptamine the result has not been ascertained.